Nower County was never a hard place to leave, but now, leaving is impossible. When drunk teenagers add letters to the Welcome to Nower County sign, making it Welcome to NoWherE County, nobody repaints it. Why bother? Everyone knows they live in the middle of nowhere.
A bizarre storm blows through the Appalachian Mountains and literally wipes Nowhere County off the map. The outside world forgets the tiny town ever existed, and no one can leave. Anyone who tries wakes up in the Dollar General Store parking lot with blinding headaches, gushing nosebleeds, and no clue what happened to them.